Top 10 Hotels in Southwest Illinois (from $57) 2026 - Competitive Prices

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Our top choices for Southwest Illinois hotels

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

1. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

KEVIN

$102 nightly

$118 total

Oct 12 - Oct 13

Total with taxes and fees

A hotel room with a large bathtub, a bed, a desk, a chair, and a sofa.

A swimming pool with lounge chairs and a brick building with a covered entrance.

A gym with treadmills, stationary bikes, and elliptical machines.

A room with a large bathtub, a desk with a chair, a lamp, and a small table with towels.

2. Super 8 by Wyndham O'Fallon

O'Fallon

Sara

$54 nightly

$62 total

Oct 13 - Oct 14

Total with taxes and fees

A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.

A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.

A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.

3. Seasons Inn & Suites Highland

Highland

Jeffrey

$94 nightly

$104 total

Sep 27 - Sep 28

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A breakfast setup with a flat iron griddle, a coffee machine, and a sign indicating fresh pancakes are available.

A modern hotel room with a blue sofa, a small table, a blue chair, a large window, and a framed artwork on the wall.

A hotel reception desk with a modern design, a digital display, and a sign for the Holiday Inn Express & Suites.

4. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

O'Fallon

Anna-Leigh

$103 nightly

$114 total

Oct 25 - Oct 26

Total with taxes and fees

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

A modern hotel room with a living area, a kitchenette, and a door leading to another room.

5. Best Western Plus MidAmerica Hotel

Mascoutah

Danny

$110 nightly

$125 total

Sep 27 - Sep 28

Total with taxes and fees

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

A hotel room with two beds, a desk, and a window with a view.

A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.

A compact kitchenette with a refrigerator and an ice dispenser.

6. Best Western U. S. Inn

Nashville

Arilla

$110 nightly

$120 total

Oct 1 - Oct 2

Total with taxes and fees

A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.

A Super 8 motel with a covered entrance, outdoor seating, and a vending machine.

A reception area with a counter, framed certificates, a clock, and a checkered floor.

A conference room with a TV, a door, and a window with blinds.

7. Super 8 by Wyndham Okawville

Okawville

Peter

$64 nightly

$68 total

Oct 6 - Oct 7

Total with taxes and fees

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs arranged around the pool area.

A hotel room with a bed, desk, chair, and a TV.

A modern kitchen with a central island, overhead pendant lights, and a dining area with wooden chairs and a table.

A living room with a fireplace, a sofa, a coffee table, and a lamp.

8. Sleep Inn O'Fallon near I-64

O'Fallon

Robert

$68 nightly

$78 total

Sep 29 - Sep 30

Total with taxes and fees

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

A modern hotel lobby with a seating area, a reception desk, and a 'Treats' sign in the background.

A reception desk with a "Welcome to the Prairie State" sign, a receptionist, and a digital display.

A snack and treat section with shelves stocked with various snacks, a 'Welcome to our store' sign, and a 'Treats' sign.

9. Hampton Inn O'Fallon

O'Fallon

Mary

$114 nightly

$132 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious lobby with a fireplace, a large painting, and multiple hanging light fixtures.

A hotel room with a kitchenette, a bed, a desk, and a television.

A buffet setup with various food stations, a coffee machine, and a menu board.

A hotel with a courtyard featuring outdoor seating and a stone facade.

10. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

O'Fallon

Roxana

$114 nightly

$132 total

Oct 11 - Oct 12

Total with taxes and fees

A breakfast bar with a coffee machine, a cereal dispenser, and a fruit display.

A hotel room with two beds, a desk, a chair, and a window with curtains.

Two HP desktop computers with keyboards and mice on a granite countertop.

A hotel entrance with a sign reading "La Quinta Inn & Suites".

11. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

O'Fallon

Tahjae

$72 nightly

$83 total

Sep 29 - Sep 30

Total with taxes and fees

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

A gym with weightlifting equipment, treadmills, and a mirrored wall.

A modern living room with a fireplace, comfortable seating, and a television.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a view of the outdoors.

12. Fairfield Inn & Suites by Marriott O'Fallon, IL

O'Fallon

Mohamad

$127 nightly

$146 total

Oct 11 - Oct 12

Total with taxes and fees

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

A spacious lobby with a large seating area, a reception desk, and a television.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

13. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

$139 nightly

$156 total

Sep 27 - Sep 28

Total with taxes and fees

A modern hotel room with a bed, a sofa, a desk, and a ceiling fan.

A modern living room with a sofa, a coffee table, a lamp, and a ceiling fan.

An indoor swimming pool with lounge chairs and a sign indicating no diving.

A kitchen area with a coffee machine, toaster, and refrigerator.

14. Comfort Inn & Suites O'Fallon - St. Louis Area

O'Fallon

Lawrence

$79 nightly

$91 total

Oct 5 - Oct 6

Total with taxes and fees

A hotel room with two beds, a large window with curtains, a flat-screen TV, and a built-in air conditioning unit.

A hotel lobby with a clear entrance, a sign indicating the lobby, and a parking area with cars.

A hotel room with a kitchenette, a desk, a chair, a bed, and a window with curtains.

15. Extended Stay America Select Suites - St. Louis - O' Fallon, IL

O'Fallon

Lavenda

$91 nightly

$105 total

Oct 19 - Oct 20

Total with taxes and fees

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A patio area with outdoor seating, including chairs and tables, and a covered area with umbrellas.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.

16. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Jeremy

$106 nightly

$118 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with two beds, a desk, a TV, and a window with blinds.

A hotel room with a red sofa, a small wooden table, a TV, and a desk with a chair.

A compact kitchen with wooden cabinets, a microwave, a stainless steel refrigerator, and a sink.

A reception area with a counter, seating, and a view of the parking lot.

17. Welcome Suites

O'Fallon

Osazuwa

$65 nightly

$75 total

Sep 27 - Sep 28

Total with taxes and fees

An outdoor seating area with a fire feature, cushioned seating, and a bar area.

A modern self-service breakfast area with a refrigerated drink dispenser, a variety of beverages, and a selection of fruits and pastries.

A hotel reception area with a wooden reception desk, a minibar, and a refrigerator stocked with beverages and snacks.

An indoor swimming pool with clear water, marked depth lines, and a 'No Diving' sign.

18. TownePlace Suites by Marriott St. Louis O'Fallon

O'Fallon

John

$140 nightly

$162 total

Oct 11 - Oct 12

Total with taxes and fees

A kitchen with granite countertops, wooden cabinets, a coffee maker, a microwave, and a potted plant.

A Super 8 motel with a two-story structure, a covered entrance, and a parking lot.

A small, cozy kitchen with a round table and four chairs, wooden cabinets, a microwave, and a coffee maker.

A hotel room with a bed, two bedside lamps, a chair, a desk, and a large window with curtains.

19. Super 8 by Wyndham Du Quoin

Du Quoin

Wendy

$84 nightly

$93 total

Oct 12 - Oct 13

Total with taxes and fees

A white door with the number 16, a mailbox, and a small light fixture on the left.

A hotel room with two beds, a desk, and a chair. There are framed pictures on the walls and a lamp on the desk.

A motel with a single-story structure, a visible entrance, and a parking lot.

A bathroom with a bathtub, toilet, and a shower curtain.

20. Lighthouse Lodge

Pocahontas

Danica

$87 nightly

$92 total

Sep 26 - Sep 27

Total with taxes and fees

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Stay near popular Southwest Illinois attractions

Giant City State Park

9.2/10 (141 reviews)

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

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World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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O'Fallon Family Sports Park

8.6/10 (137 reviews)

Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.

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DuQuoin State Fairgrounds

8.2/10 (95 reviews)

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

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Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois

A tall, modern tower with balconies, set against a clear blue sky.

Top Southwest Illinois Hotel Reviews

Super 8 by Wyndham O'Fallon

10/10 Excellent

"Clean"

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent

"Breakfast"

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Great Staff, very professional and helpful"

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Everything was excellent at this hotel. My wife can be very picky but she thought it was all great."

Comfort Suites Mount Vernon

10/10 Excellent

"Very clean & updated. Great location"

Radisson Hotel Fairview Heights - St. Louis

8/10 Good

"clean pretty quiet and close to i64"

Walker's Bluff Casino Resort

8/10 Good

"Staff was very helpful checking me and my dog in. Was just passing by for the night was a good place to stop and recharge before continuing my journey. Would definitely visit again if life takes me in the area"

Country Inn & Suites by Radisson, Fairview Heights, IL

10/10 Excellent

"Was perfect for our plans. Hotel was clean with friendly staff."

Baymont by Wyndham Marion

8/10 Good

"although not new the hotel was in good condition and the price was acceptable"

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

$53 nightly

$61 total

Oct 11 - Oct 12

Total with taxes and fees

6.4/10 (976 reviews)

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

$54 nightly

$62 total

Oct 13 - Oct 14

Total with taxes and fees

6.6/10 (1,108 reviews)

Super 8 by Wyndham Collinsville St. Louis

2 Gateway Dr Collinsville IL

$68 nightly

$78 total

Sep 28 - Sep 29

Total with taxes and fees

7/10 Good! (1,001 reviews)

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL

$84 nightly

$95 total

Sep 27 - Sep 28

Total with taxes and fees

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

$95 nightly

$109 total

Oct 18 - Oct 19

Total with taxes and fees

Baymont by Wyndham Marion

2608 W Main St Marion IL

$96 nightly

$115 total

Oct 25 - Oct 26

Total with taxes and fees

8.4/10 Very Good! (1,089 reviews)

Hotels in Southwest Illinois with star-rating

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Go beyond your typical stay in Southwest Illinois

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Our top choices for Southwest Illinois hotels

1. Drury Inn & Suites St. Louis O'Fallon, IL

2. Super 8 by Wyndham O'Fallon

3. Seasons Inn & Suites Highland

4. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

5. Best Western Plus MidAmerica Hotel

6. Best Western U. S. Inn

7. Super 8 by Wyndham Okawville

8. Sleep Inn O'Fallon near I-64

9. Hampton Inn O'Fallon

10. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

11. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

12. Fairfield Inn & Suites by Marriott O'Fallon, IL

13. Best Western Plus Centralia Hotel & Suites

14. Comfort Inn & Suites O'Fallon - St. Louis Area

15. Extended Stay America Select Suites - St. Louis - O' Fallon, IL

16. Holiday Inn Express Hotel & Suites Sparta by IHG

17. Welcome Suites

18. TownePlace Suites by Marriott St. Louis O'Fallon

19. Super 8 by Wyndham Du Quoin

20. Lighthouse Lodge

Stay near popular Southwest Illinois attractions

Giant City State Park

World Wide Technology Raceway

O'Fallon Family Sports Park

DuQuoin State Fairgrounds

Learn more about Southwest Illinois

Top Southwest Illinois Hotel Reviews

Super 8 by Wyndham O'Fallon

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Plaza Hotel Mt. Vernon

Comfort Suites Mount Vernon

Radisson Hotel Fairview Heights - St. Louis

Walker's Bluff Casino Resort

Country Inn & Suites by Radisson, Fairview Heights, IL

Baymont by Wyndham Marion

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham Collinsville St. Louis

Best Western St. Louis Fairview Heights

Comfort Inn Edwardsville - St. Louis

Baymont by Wyndham Marion

Hotels in Southwest Illinois with star-rating

Explore a world of travel with Expedia